Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50481614'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50481614 (CHEMBL589907) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](=O)-[#7]S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H33NO3S/c1-19(2)11-8-12-20(3)13-9-14-21(4)15-10-18-23(25)24-28(26,27)22-16-6-5-7-17-22/h5-7,11,13,15-17H,8-10,12,14,18H2,1-4H3,(H,24,25)/b20-13+,21-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche de Gif-sur-Yvette Curated by ChEMBL					Assay Description Inhibition of human recombinant FTase by fluorescent-based assay				Bioorg Med Chem 18: 543-56 (2010) Article DOI: 10.1016/j.bmc.2009.12.017 BindingDB Entry DOI: 10.7270/Q2VM4G37
					More data for this Ligand-Target Pair