Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha' and Ligand = 'BDBM50498788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50498788 (CHEMBL3623717) Show SMILES CSCC[C@H](NC(=O)CCn1c2ccccc2c2ccccc12)C(O)=O |r| Show InChI InChI=1S/C20H22N2O3S/c1-26-13-11-16(20(24)25)21-19(23)10-12-22-17-8-4-2-6-14(17)15-7-3-5-9-18(15)22/h2-9,16H,10-13H2,1H3,(H,21,23)(H,24,25)/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Alexandru Ioan Cuza University Curated by ChEMBL					Assay Description Inhibition of recombinant human FTase using FPP/dansyl-GCVLS as substrate measured for 15 mins by fluorimetric analysis				Bioorg Med Chem Lett 25: 4447-52 (2015) Article DOI: 10.1016/j.bmcl.2015.09.008 BindingDB Entry DOI: 10.7270/Q2XS5ZDS
					More data for this Ligand-Target Pair