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Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase C iota type' and Ligand = 'BDBM50455587'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein kinase C iota type


(Homo sapiens (Human))		BDBM50455587
PNG
(CHEMBL4205851)
Show SMILES NCc1ccc(cc1)-n1cnc2ccc(cc12)-c1ccnc2[nH]ccc12
Show InChI InChI=1S/C21H17N5/c22-12-14-1-4-16(5-2-14)26-13-25-19-6-3-15(11-20(19)26)17-7-9-23-21-18(17)8-10-24-21/h1-11,13H,12,22H2,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 800n/an/an/an/an/an/a



Agency for Science, Technology and Research (A*STAR)

Curated by ChEMBL


Assay Description
Inhibition of full-length N-terminal GST-fused human PKC-iota expressed in baculovirus expression system using (5FAM) RFARKGSLRQKNV as substrate afte...

J Med Chem 61: 4386-4396 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00060
BindingDB Entry DOI: 10.7270/Q2V69N5Z
More data for this
Ligand-Target Pair