Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase C theta type' and Ligand = 'BDBM35121'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM35121 (5-vinyl-3-pyridinecarbonitrile, 11c) Show SMILES Cc1c(Nc2c(\C=C\CCCN3CCOCC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H27N5O/c1-18-21-8-9-27-23(21)7-6-22(18)28-24-19(16-26-17-20(24)15-25)5-3-2-4-10-29-11-13-30-14-12-29/h3,5-9,16-17,27H,2,4,10-14H2,1H3,(H,26,28)/b5-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	7.2	22
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
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