Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein kinase C theta type' and Ligand = 'BDBM35132'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM35132 (5-vinyl-3-pyridinecarbonitrile, 15b) Show SMILES Cc1c(Nc2c(\C=C\CCN3CCC(O)CC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H27N5O/c1-17-21-7-10-27-23(21)6-5-22(17)28-24-18(15-26-16-19(24)14-25)4-2-3-11-29-12-8-20(30)9-13-29/h2,4-7,10,15-16,20,27,30H,3,8-9,11-13H2,1H3,(H,26,28)/b4-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	7.2	22
Wyeth Research					Assay Description All IC50s were measured by using a modified IMAP protocol from Molecular Devices. The kinase reaction was carried out in a Corning Costar 384 well pl...				Bioorg Med Chem 17: 7933-48 (2009) Article DOI: 10.1016/j.bmc.2009.10.020 BindingDB Entry DOI: 10.7270/Q2M043RT
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