Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Protein mono-ADP-ribosyltransferase PARP10' and Ligand = 'BDBM50503858'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI InChI=1S/C17H15N3O/c1-10-13(2-3-15-14(10)5-7-19-17(15)21)12-8-11-4-6-18-16(11)20-9-12/h2-4,6,8-9H,5,7H2,1H3,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair
Protein mono-ADP-ribosyltransferase PARP10 (Homo sapiens (Human))	BDBM50503858 (CHEMBL4462418) Show SMILES Cc1c2CCNC(=O)c2ccc1-c1cnc2[nH]ccc2c1 Show InChI InChI=1S/C17H15N3O/c1-10-13(2-3-15-14(10)5-7-19-17(15)21)12-8-11-4-6-18-16(11)20-9-12/h2-4,6,8-9H,5,7H2,1H3,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429 BindingDB Entry DOI: 10.7270/Q2HX1GXV
					More data for this Ligand-Target Pair