Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein mono-ADP-ribosyltransferase PARP14' and Ligand = 'BDBM434484'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein mono-ADP-ribosyltransferase PARP14 (Homo sapiens (Human))	BDBM434484 (US10562891, Example 398 | US11008308, Example 398) Show SMILES CCC(=O)N1CCC(COc2cc(F)c3c(c2)nc(CSC2CCOCC2)[nH]c3=O)CC1 Show InChI InChI=1S/C23H30FN3O4S/c1-2-21(28)27-7-3-15(4-8-27)13-31-16-11-18(24)22-19(12-16)25-20(26-23(22)29)14-32-17-5-9-30-10-6-17/h11-12,15,17H,2-10,13-14H2,1H3,(H,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ribon Therapeutics Inc. US Patent					Assay Description Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...				US Patent US11008308 (2021) BindingDB Entry DOI: 10.7270/Q28D00C5
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