Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Protein-serine O-palmitoleoyltransferase porcupine' and Ligand = 'BDBM50197194'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50197194 (CHEMBL3907027) Show SMILES Cc1cc(ccn1)-c1ccc(CNC(=O)c2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C26H22N2O/c1-19-17-25(15-16-27-19)23-9-7-20(8-10-23)18-28-26(29)24-13-11-22(12-14-24)21-5-3-2-4-6-21/h2-17H,18H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Soochow University Curated by ChEMBL					Assay Description Inhibition of porcupine in mouse L Wnt3A cells co-cultured with HEK293 cells after 48 hrs by Super-top flash reporter gene assay				Bioorg Med Chem 24: 5861-5872 (2016) Article DOI: 10.1016/j.bmc.2016.09.041 BindingDB Entry DOI: 10.7270/Q2HQ41VN
					More data for this Ligand-Target Pair