Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proteinase-activated receptor 1' and Ligand = 'BDBM50222037'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50222037 ((1R,3aR,4aS,8aS,9S,9aS)-dodecahydro-1-methyl-3-oxo...) Show SMILES C[C@H]1OC(=O)[C@@H]2C[C@@H]3CN(CC[C@H]3[C@H](C=Cc3ccc(cn3)-c3cccc(F)c3)[C@H]12)C(N)=O |w:15.16| Show InChI InChI=1S/C26H28FN3O3/c1-15-24-22(8-7-20-6-5-17(13-29-20)16-3-2-4-19(27)11-16)21-9-10-30(26(28)32)14-18(21)12-23(24)25(31)33-15/h2-8,11,13,15,18,21-24H,9-10,12,14H2,1H3,(H2,28,32)/t15-,18-,21-,22+,23-,24+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membrane				J Med Chem 50: 5147-60 (2007) Article DOI: 10.1021/jm070704k BindingDB Entry DOI: 10.7270/Q2SN08PK
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