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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50037987'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50037987
PNG
((R)-N-(1-Carbamimidoyl-piperidin-3-ylmethyl)-3-(1H...)
Show SMILES NC(=N)N1CCCC(CNC(=O)[C@@H](Cc2c[nH]c3ccccc23)NS(=O)(=O)c2ccc3ccccc3c2)C1
Show InChI InChI=1S/C28H32N6O3S/c29-28(30)34-13-5-6-19(18-34)16-32-27(35)26(15-22-17-31-25-10-4-3-9-24(22)25)33-38(36,37)23-12-11-20-7-1-2-8-21(20)14-23/h1-4,7-12,14,17,19,26,31,33H,5-6,13,15-16,18H2,(H3,29,30)(H,32,35)/t19?,26-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 18n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
In vitro binding affinity by measuring the inhibition of human thrombin

J Med Chem 37: 3889-901 (1994)


BindingDB Entry DOI: 10.7270/Q25X29KK
More data for this
Ligand-Target Pair