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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50215430'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM50215430
PNG
(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Show SMILES Nc1cccc(c1)-c1c(Cl)nc(NC2CCC2)c(=O)n1CC(=O)NCc1ccnc(N)n1
Show InChI InChI=1S/C21H23ClN8O2/c22-18-17(12-3-1-4-13(23)9-12)30(20(32)19(29-18)27-14-5-2-6-14)11-16(31)26-10-15-7-8-25-21(24)28-15/h1,3-4,7-9,14H,2,5-6,10-11,23H2,(H,26,31)(H,27,29)(H2,24,25,28)
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PC sid
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Similars
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of factor 2a

Bioorg Med Chem Lett 17: 4568-74 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.090
BindingDB Entry DOI: 10.7270/Q2319VK8
More data for this
Ligand-Target Pair