Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene Wnt-3 (Homo sapiens (Human)) | BDBM50294805 (CHEMBL562252 | N-(2,6-Difluoro-phenyl)-4-((1R,2S,6...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >2.50E+4 | n/a | n/a | n/a | n/a |
The University of Texas Southwestern Medical Center at Dallas Curated by ChEMBL | Assay Description Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay | Bioorg Med Chem Lett 19: 3825-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.040 BindingDB Entry DOI: 10.7270/Q2DZ08BS | |||||||||||
More data for this Ligand-Target Pair |