Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-3' and Ligand = 'BDBM50294821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-3 (Homo sapiens (Human))	BDBM50294821 (4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES Cc1cc(ccc1-n1c(O)c2[C@H]3C[C@H](C=C3)c2c1O)C(=O)Nc1cccc2cccnc12 |r,wU:13.13,11.12,c:15,(-4.62,-35.31,;-3.86,-36.65,;-2.32,-36.66,;-1.55,-37.99,;-2.32,-39.33,;-3.86,-39.33,;-4.63,-37.99,;-6.17,-37.98,;-7.08,-39.24,;-6.61,-40.71,;-8.55,-38.76,;-9.9,-39.42,;-9.48,-37.94,;-9.87,-36.45,;-11.21,-37.21,;-11.21,-38.75,;-8.55,-37.22,;-7.08,-36.75,;-6.61,-35.28,;-.01,-38,;.76,-36.67,;.76,-39.34,;2.3,-39.3,;3.04,-37.95,;4.57,-37.9,;5.38,-39.21,;4.64,-40.58,;5.44,-41.88,;4.71,-43.23,;3.17,-43.28,;2.37,-41.96,;3.1,-40.61,)| Show InChI InChI=1S/C26H21N3O3/c1-14-12-18(24(30)28-19-6-2-4-15-5-3-11-27-23(15)19)9-10-20(14)29-25(31)21-16-7-8-17(13-16)22(21)26(29)32/h2-12,16-17,31-32H,13H2,1H3,(H,28,30)/t16-,17+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center at Dallas Curated by ChEMBL					Assay Description Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay				Bioorg Med Chem Lett 19: 3825-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.040 BindingDB Entry DOI: 10.7270/Q2DZ08BS
					More data for this Ligand-Target Pair