Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-3' and Ligand = 'BDBM50294822'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-3 (Homo sapiens (Human))	BDBM50294822 (4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES COc1cc(ccc1-n1c(O)c2[C@H]3C[C@H](C=C3)c2c1O)C(=O)Nc1cccc2cccnc12 |r,wU:14.14,12.13,c:16,(18.67,-31.94,;17.9,-33.27,;18.66,-34.61,;20.2,-34.62,;20.97,-35.95,;20.2,-37.29,;18.66,-37.29,;17.89,-35.95,;16.35,-35.94,;15.44,-37.2,;15.91,-38.67,;13.97,-36.72,;12.62,-37.38,;13.04,-35.9,;12.65,-34.41,;11.31,-35.17,;11.31,-36.71,;13.97,-35.18,;15.44,-34.71,;15.91,-33.24,;22.51,-35.96,;23.28,-34.63,;23.27,-37.3,;24.81,-37.26,;25.56,-35.91,;27.09,-35.86,;27.9,-37.17,;27.16,-38.54,;27.96,-39.84,;27.23,-41.19,;25.69,-41.23,;24.89,-39.92,;25.62,-38.57,)| Show InChI InChI=1S/C26H21N3O4/c1-33-20-13-17(24(30)28-18-6-2-4-14-5-3-11-27-23(14)18)9-10-19(20)29-25(31)21-15-7-8-16(12-15)22(21)26(29)32/h2-11,13,15-16,31-32H,12H2,1H3,(H,28,30)/t15-,16+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center at Dallas Curated by ChEMBL					Assay Description Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay				Bioorg Med Chem Lett 19: 3825-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.040 BindingDB Entry DOI: 10.7270/Q2DZ08BS
					More data for this Ligand-Target Pair