Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-3' and Ligand = 'BDBM50294828'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-3 (Homo sapiens (Human))	BDBM50294828 (4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*...) Show SMILES Cc1ccnc2c(NC(=O)[C@H]3CC[C@@H](CC3)N3C(=O)[C@H]4[C@@H]5C[C@@H](C=C5)[C@H]4C3=O)cccc12 |r,wU:20.21,22.22,10.9,wD:19.19,25.28,13.16,c:24,(7.08,-13.51,;5.54,-13.51,;4.77,-14.84,;3.22,-14.85,;2.45,-13.51,;3.22,-12.18,;2.45,-10.84,;.9,-10.84,;.14,-9.5,;.91,-8.17,;-1.41,-9.5,;-2.17,-10.83,;-3.71,-10.83,;-4.48,-9.49,;-3.71,-8.16,;-2.17,-8.16,;-6.02,-9.49,;-6.93,-8.25,;-6.46,-6.78,;-8.39,-8.73,;-9.72,-7.96,;-9.33,-9.44,;-9.75,-10.92,;-11.06,-10.26,;-11.06,-8.72,;-8.4,-10.27,;-6.93,-10.75,;-6.46,-12.21,;3.22,-9.51,;4.77,-9.51,;5.54,-10.85,;4.77,-12.18,)| Show InChI InChI=1S/C26H27N3O3/c1-14-11-12-27-23-19(14)3-2-4-20(23)28-24(30)15-7-9-18(10-8-15)29-25(31)21-16-5-6-17(13-16)22(21)26(29)32/h2-6,11-12,15-18,21-22H,7-10,13H2,1H3,(H,28,30)/t15-,16-,17+,18-,21-,22+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
The University of Texas Southwestern Medical Center at Dallas Curated by ChEMBL					Assay Description Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assay				Bioorg Med Chem Lett 19: 3825-7 (2009) Article DOI: 10.1016/j.bmcl.2009.04.040 BindingDB Entry DOI: 10.7270/Q2DZ08BS
					More data for this Ligand-Target Pair