Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM148325'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM148325 (US8962637, 137 | US8962637, 51) Show SMILES CN1CCN(Cc2cccc(Nc3ncc4CN(CCc4n3)c3cc(NC(=O)c4cccc(c4)C(F)(F)F)ccc3C)c2)CC1 Show InChI InChI=1S/C34H36F3N7O/c1-23-9-10-29(39-32(45)25-6-4-7-27(18-25)34(35,36)37)19-31(23)44-12-11-30-26(22-44)20-38-33(41-30)40-28-8-3-5-24(17-28)21-43-15-13-42(2)14-16-43/h3-10,17-20H,11-16,21-22H2,1-2H3,(H,39,45)(H,38,40,41)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Debiopharm S.A.; Aurigene Discovery Technologies Ltd. US Patent					Assay Description Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...				US Patent US8962637 (2015) BindingDB Entry DOI: 10.7270/Q2MS3RGN
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