Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM148447'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM148447 (US8962637, 178) Show SMILES Cc1ccc(NC(=O)c2cccc(c2)C(F)(F)F)cc1N1CCc2nc(Nc3ccc(cc3)N3CCNCC3)ncc2C1=O Show InChI InChI=1S/C32H30F3N7O2/c1-20-5-6-24(38-29(43)21-3-2-4-22(17-21)32(33,34)35)18-28(20)42-14-11-27-26(30(42)44)19-37-31(40-27)39-23-7-9-25(10-8-23)41-15-12-36-13-16-41/h2-10,17-19,36H,11-16H2,1H3,(H,38,43)(H,37,39,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Debiopharm S.A.; Aurigene Discovery Technologies Ltd. US Patent					Assay Description Compounds were screened in the TR-FRET assay for JAK2 and c-Src kinase inhibition. Ultra light poly GT (Perkin Elmer) was used as the substrate for J...				US Patent US8962637 (2015) BindingDB Entry DOI: 10.7270/Q2MS3RGN
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