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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM163700'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM163700
PNG
(N-(5-((4-((4-ethylpiperazin-1-yl)methyl)-3-(triflu...)
Show SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cncc(c4)-c4cnn(C)c4)c3)cc2C(F)(F)F)CC1
Show InChI InChI=1S/C32H34F3N7O2/c1-4-41-9-11-42(12-10-41)20-23-7-8-27(15-28(23)32(33,34)35)38-30(43)22-6-5-21(2)29(14-22)39-31(44)25-13-24(16-36-17-25)26-18-37-40(3)19-26/h5-8,13-19H,4,9-12,20H2,1-3H3,(H,38,43)(H,39,44)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a



Dana-Farber Cancer Institute



Assay Description
The enzymatic activities DDR2 were tested in LanthaScreen binding assays. The protocol is available from Life Technologies.

ACS Chem Biol 10: 2687-96 (2015)


Article DOI: 10.1021/acschembio.5b00655
BindingDB Entry DOI: 10.7270/Q2SX6BZ1
More data for this
Ligand-Target Pair