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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50074711'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50074711
PNG
(CHEMBL355759 | Phosphoric acid mono-[4-((5S,8R,11S...)
Show SMILES CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CCCCNC(=O)[C@H]2CCCN2C(=O)[C@H](CC2CCCCC2)NC(=O)[C@@H](CC(N)=O)NC1=O)NC(C)=O
Show InChI InChI=1S/C40H61N8O12P/c1-23(2)34-39(55)45-30(22-33(41)50)36(52)46-31(21-25-10-5-4-6-11-25)40(56)48-19-9-13-32(48)38(54)42-18-8-7-12-28(43-24(3)49)35(51)44-29(37(53)47-34)20-26-14-16-27(17-15-26)60-61(57,58)59/h14-17,23,25,28-32,34H,4-13,18-22H2,1-3H3,(H2,41,50)(H,42,54)(H,43,49)(H,44,51)(H,45,55)(H,46,52)(H,47,53)(H2,57,58,59)/t28-,29+,30+,31-,32+,34-/m0/s1
PDB
MMDB

KEGG

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PC cid
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Similars
Article
PubMed
n/an/a>1.50E+5n/an/an/an/an/an/a



Novartis Forschungsinstitut

Curated by ChEMBL


Assay Description
Inhibitory activity against binding of Src protein tryrosine kinase SH2 domain to biotinylated EPQY*EEIPI Peptide by ELISA.

J Med Chem 42: 971-80 (1999)


Article DOI: 10.1021/jm9811007
BindingDB Entry DOI: 10.7270/Q28S4P35
More data for this
Ligand-Target Pair