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Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50279742'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50279742
PNG
(CHEMBL4166840)
Show SMILES N#Cc1ccc(cc1)-c1nc(Nc2cc([nH]n2)C2CC2)c2ccccc2n1
Show InChI InChI=1S/C21H16N6/c22-12-13-5-7-15(8-6-13)20-23-17-4-2-1-3-16(17)21(25-20)24-19-11-18(26-27-19)14-9-10-14/h1-8,11,14H,9-10H2,(H2,23,24,25,26,27)
PDB
MMDB

KEGG

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PC cid
PC sid
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Similars
Article
PubMed
 18n/an/an/an/an/an/an/an/a



Vertex Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of recombinant SRC (unknown origin) using polyE4Y as substrate by pyruvate kinase-lactate dehydrogenase coupled assay

ACS Med Chem Lett 8: 1224-1229 (2017)


Article DOI: 10.1021/acsmedchemlett.7b00239
BindingDB Entry DOI: 10.7270/Q2183910
More data for this
Ligand-Target Pair