Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM6199'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6199 (Benzofuran deriv. 8 | N-(1-Benzofuran-4-yl)-6-meth...) Show SMILES COc1cc2c(Nc3cccc4occc34)ncnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C24H26N4O4/c1-29-22-14-18-20(15-23(22)31-10-3-7-28-8-12-30-13-9-28)25-16-26-24(18)27-19-4-2-5-21-17(19)6-11-32-21/h2,4-6,11,14-16H,3,7-10,12-13H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	22
AstraZeneca					Assay Description This assay determines the ability of test compounds to inhibit Src kinase activity that catalyzes the transfer of the terminal phosphate to the immob...				J Med Chem 47: 871-87 (2004) Article DOI: 10.1021/jm030317k BindingDB Entry DOI: 10.7270/Q2930RCG
					More data for this Ligand-Target Pair