Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM25196'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM25196 (4-[(5-hydroxy-2-methylphenyl)amino]-N-(propan-2-yl...) Show SMILES CC(C)NC(=O)c1ccc2nccc(Nc3cc(O)ccc3C)c2c1 Show InChI InChI=1S/C20H21N3O2/c1-12(2)22-20(25)14-5-7-17-16(10-14)18(8-9-21-17)23-19-11-15(24)6-4-13(19)3/h4-12,24H,1-3H3,(H,21,23)(H,22,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	7.4	22
GlaxoSmithKline					Assay Description The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...				Bioorg Med Chem Lett 17: 5886-93 (2007) Article DOI: 10.1016/j.bmcl.2007.07.104 BindingDB Entry DOI: 10.7270/Q2H1309S
					More data for this Ligand-Target Pair