Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM434989'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM434989 (US10584114, Compound 101 | US11279688, Compound 10...) Show SMILES Cc1cc(Nc2cc(C)nc(n2)[C@H]2CC[C@@H](CC2)C(=O)NCc2ccc(nc2)-n2cccn2)n[nH]1 |r,wU:12.12,wD:15.19,(-12.54,-.74,;-11.01,-.9,;-9.98,.24,;-8.57,-.39,;-7.24,.38,;-5.9,-.39,;-5.9,-1.93,;-4.57,-2.7,;-4.57,-4.24,;-3.24,-1.93,;-3.24,-.39,;-4.57,.38,;-1.9,.38,;-1.9,1.93,;-.57,2.69,;.77,1.93,;.77,.38,;-.57,-.38,;2.1,2.7,;2.1,4.24,;3.43,1.93,;4.77,2.7,;6.1,1.93,;7.43,2.7,;8.77,1.93,;8.77,.39,;7.43,-.38,;6.1,.39,;10.1,-.38,;11.51,.24,;12.54,-.9,;11.77,-2.24,;10.26,-1.92,;-8.73,-1.92,;-10.24,-2.24,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In each well of a 384-well plate, 7.5 nM-10 nM of wild type RET (ProQinase 1090-0000-1) was incubated in a total of 12.5 μL of buffer (100 mM HE...				Citation and Details BindingDB Entry DOI: 10.7270/Q2B56NZ4
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM434989 (US10584114, Compound 101 | US11279688, Compound 10...) Show SMILES Cc1cc(Nc2cc(C)nc(n2)[C@H]2CC[C@@H](CC2)C(=O)NCc2ccc(nc2)-n2cccn2)n[nH]1 |r,wU:12.12,wD:15.19,(-12.54,-.74,;-11.01,-.9,;-9.98,.24,;-8.57,-.39,;-7.24,.38,;-5.9,-.39,;-5.9,-1.93,;-4.57,-2.7,;-4.57,-4.24,;-3.24,-1.93,;-3.24,-.39,;-4.57,.38,;-1.9,.38,;-1.9,1.93,;-.57,2.69,;.77,1.93,;.77,.38,;-.57,-.38,;2.1,2.7,;2.1,4.24,;3.43,1.93,;4.77,2.7,;6.1,1.93,;7.43,2.7,;8.77,1.93,;8.77,.39,;7.43,-.38,;6.1,.39,;10.1,-.38,;11.51,.24,;12.54,-.9,;11.77,-2.24,;10.26,-1.92,;-8.73,-1.92,;-10.24,-2.24,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description In each well of a 384-well plate, 7.5 nM-10 nM of wild type RET (ProQinase 1090-0000-1) was incubated in a total of 12.5 μL of buffer (100 mM HE...				US Patent US10584114 (2020) BindingDB Entry DOI: 10.7270/Q27083V8
					More data for this Ligand-Target Pair