Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50165910'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50165910 (CHEMBL3799843) Show SMILES COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C23H27FN4O3/c1-14-19(29)5-4-17(24)22(14)27-23-16-10-20(30-3)21(11-18(16)25-13-26-23)31-12-15-6-8-28(2)9-7-15/h4-5,10-11,13,15,29H,6-9,12H2,1-3H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal GST fused human RET (658 to 1114 amino acid residue) using CSKtide as substrate expressed in baculovirus preincubated for 15...				Bioorg Med Chem Lett 26: 2724-9 (2016) Article DOI: 10.1016/j.bmcl.2016.03.100 BindingDB Entry DOI: 10.7270/Q2WM1G93
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