Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret' and Ligand = 'BDBM50462229'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret (Homo sapiens (Human))	BDBM50462229 (CHEMBL4242953) Show SMILES Nc1c(oc2ccccc2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H10ClNO2/c16-10-7-5-9(6-8-10)15-13(17)14(18)11-3-1-2-4-12(11)19-15/h1-8H,17H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli "Federico II" Curated by ChEMBL					Assay Description Inhibition of wild type recombinant human RET using peptide as substrate by fluorimetric analysis				Eur J Med Chem 150: 491-505 (2018) Article DOI: 10.1016/j.ejmech.2018.02.080 BindingDB Entry DOI: 10.7270/Q2B27XXB
					More data for this Ligand-Target Pair