BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase receptor Ret [658-1114]' and Ligand = 'BDBM296581'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase receptor Ret [658-1114] (Homo sapiens (Human))	BDBM296581 (US10112942, Example 315 \| US10137124, Example 315 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE-TK assay techn...				US Patent US10555944 (2020) BindingDB Entry DOI: 10.7270/Q279473N
Eli Lilly and Company US Patent					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase receptor Ret [658-1114] (Homo sapiens (Human))	BDBM296581 (US10112942, Example 315 \| US10137124, Example 315 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Inc. US Patent					Assay Description Compounds of Formula I were screened for their ability to inhibit wildtype and V804M mutant RET kinase using CisBio's HTRF KinEASE -TK assay tech...				US Patent US10172851 (2019) BindingDB Entry DOI: 10.7270/Q2GM89CV
Array BioPharma Inc. US Patent					More data for this Ligand-Target Pair