Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50046225'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50046225 (2-Amino-7-(3,4-dichloro-benzyl)-3,5-dihydro-pyrrol...) Show SMILES Nc1nc2c(Cc3ccc(Cl)c(Cl)c3)c[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C13H10Cl2N4O/c14-8-2-1-6(4-9(8)15)3-7-5-17-11-10(7)18-13(16)19-12(11)20/h1-2,4-5,17H,3H2,(H3,16,18,19,20)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphate				J Med Chem 36: 55-69 (1993) BindingDB Entry DOI: 10.7270/Q2B27TCX
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bos taurus (bovine))	BDBM50046225 (2-Amino-7-(3,4-dichloro-benzyl)-3,5-dihydro-pyrrol...) Show SMILES Nc1nc2c(Cc3ccc(Cl)c(Cl)c3)c[nH]c2c(=O)[nH]1 Show InChI InChI=1S/C13H10Cl2N4O/c14-8-2-1-6(4-9(8)15)3-7-5-17-11-10(7)18-13(16)19-12(11)20/h1-2,4-5,17H,3H2,(H3,16,18,19,20)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of purine nucleoside phosphorylase against the enzyme from calf spleen in 1 mM phosphate				J Med Chem 36: 55-69 (1993) BindingDB Entry DOI: 10.7270/Q2B27TCX
					More data for this Ligand-Target Pair