Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Pyruvate kinase PKM' and Ligand = 'BDBM50455475'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate kinase PKM (Homo sapiens (Human))	BDBM50455475 (CHEMBL1085588) Show SMILES C[S+]([O-])c1cc2n(C)c3c(cnn(Cc4cccc(N)c4)c3=O)c2s1 Show InChI InChI=1S/C17H16N4O2S2/c1-20-13-7-14(25(2)23)24-16(13)12-8-19-21(17(22)15(12)20)9-10-4-3-5-11(18)6-10/h3-8H,9,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00981 BindingDB Entry DOI: 10.7270/Q2M330SP
					More data for this Ligand-Target Pair
Pyruvate kinase PKM (Homo sapiens (Human))	BDBM50455475 (CHEMBL1085588) Show SMILES C[S+]([O-])c1cc2n(C)c3c(cnn(Cc4cccc(N)c4)c3=O)c2s1 Show InChI InChI=1S/C17H16N4O2S2/c1-20-13-7-14(25(2)23)24-16(13)12-8-19-21(17(22)15(12)20)9-10-4-3-5-11(18)6-10/h3-8H,9,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	92	n/a	n/a	n/a	n/a
Nankai University Curated by ChEMBL					Assay Description Activation of recombinant human PKM2 expressed in Escherichia coli BL21 at 4 uM incubated for 50 mins measured over 40 mins				J Med Chem 61: 4155-4164 (2018) Article DOI: 10.1021/acs.jmedchem.8b00241 BindingDB Entry DOI: 10.7270/Q2C82CWR
					More data for this Ligand-Target Pair