Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase' and Ligand = 'BDBM182356'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human))	BDBM182356 (US9145392, 57) Show SMILES Nc1ncnc(N2CCC(CC2)c2nc(cn2CCN2CCCC2)-c2ccc(F)c(c2)C(F)(F)F)c1-c1ccc(F)cc1 Show InChI InChI=1S/C31H32F5N7/c32-23-6-3-20(4-7-23)27-28(37)38-19-39-30(27)42-13-9-21(10-14-42)29-40-26(18-43(29)16-15-41-11-1-2-12-41)22-5-8-25(33)24(17-22)31(34,35)36/h3-8,17-19,21H,1-2,9-16H2,(H2,37,38,39)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Akt (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128352 BindingDB Entry DOI: 10.7270/Q2SB49H5
					More data for this Ligand-Target Pair