Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase' and Ligand = 'BDBM224477'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Homo sapiens (Human))	BDBM224477 (US10080750, Compound 155 | US9321760, 155 | US9662...) Show SMILES NCC(N1CCN(CC1)c1ncnc(N)c1-c1ccc(F)cc1)c1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C23H23F5N6/c24-16-4-1-14(2-5-16)20-21(30)31-13-32-22(20)34-9-7-33(8-10-34)19(12-29)15-3-6-18(25)17(11-15)23(26,27)28/h1-6,11,13,19H,7-10,12,29H2,(H2,30,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Akt (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128352 BindingDB Entry DOI: 10.7270/Q2SB49H5
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