Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM112788'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM112788 (US8628961, PIT-5) Show SMILES Cc1cc(C)cc(c1)C(=O)NC(=S)Nc1c(O)cc(cc1C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C18H14F6N2O2S/c1-8-3-9(2)5-10(4-8)15(28)26-16(29)25-14-12(18(22,23)24)6-11(7-13(14)27)17(19,20)21/h3-7,27H,1-2H3,(H2,25,26,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	7.5	25
Tufts University; Council of Scientific and Industrial Research US Patent					Assay Description In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...				US Patent US8628961 (2014) BindingDB Entry DOI: 10.7270/Q2MG7N5S
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