Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50243763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243763 (6-phenyl-2-(piperidin-1-yl)-7-(4-((4-(5-(pyridin-2...) Show SMILES C(N1CCC(CC1)c1nnc([nH]1)-c1ccccn1)c1ccc(cc1)-c1nc2nc(ncc2cc1-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C37H37N9/c1-3-9-27(10-4-1)31-23-30-24-39-37(46-19-7-2-8-20-46)42-34(30)40-33(31)28-14-12-26(13-15-28)25-45-21-16-29(17-22-45)35-41-36(44-43-35)32-11-5-6-18-38-32/h1,3-6,9-15,18,23-24,29H,2,7-8,16-17,19-22,25H2,(H,41,43,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation by HTRF assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243763 (6-phenyl-2-(piperidin-1-yl)-7-(4-((4-(5-(pyridin-2...) Show SMILES C(N1CCC(CC1)c1nnc([nH]1)-c1ccccn1)c1ccc(cc1)-c1nc2nc(ncc2cc1-c1ccccc1)N1CCCCC1 Show InChI InChI=1S/C37H37N9/c1-3-9-27(10-4-1)31-23-30-24-39-37(46-19-7-2-8-20-46)42-34(30)40-33(31)28-14-12-26(13-15-28)25-45-21-16-29(17-22-45)35-41-36(44-43-35)32-11-5-6-18-38-32/h1,3-6,9-15,18,23-24,29H,2,7-8,16-17,19-22,25H2,(H,41,43,44)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation in human by C33a cells by IPKA assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair