Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50243770'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243770 (2-((S)-3-methylpiperazin-1-yl)-6-phenyl-7-(4-((4-(...) Show SMILES C[C@H]1CN(CCN1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 |r| Show InChI InChI=1S/C37H38N10/c1-25-23-47(20-17-38-25)37-40-22-30-21-31(27-7-3-2-4-8-27)33(41-34(30)43-37)28-12-10-26(11-13-28)24-46-18-14-29(15-19-46)35-42-36(45-44-35)32-9-5-6-16-39-32/h2-13,16,21-22,25,29,38H,14-15,17-20,23-24H2,1H3,(H,42,44,45)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation by HTRF assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243770 (2-((S)-3-methylpiperazin-1-yl)-6-phenyl-7-(4-((4-(...) Show SMILES C[C@H]1CN(CCN1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 |r| Show InChI InChI=1S/C37H38N10/c1-25-23-47(20-17-38-25)37-40-22-30-21-31(27-7-3-2-4-8-27)33(41-34(30)43-37)28-12-10-26(11-13-28)24-46-18-14-29(15-19-46)35-42-36(45-44-35)32-9-5-6-16-39-32/h2-13,16,21-22,25,29,38H,14-15,17-20,23-24H2,1H3,(H,42,44,45)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt1 (unknown origin) phosphorylation in human by C33a cells by IPKA assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair