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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50322411'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50322411
PNG
(CHEMBL1171485 | N-((3-amino-1-(5-methyl-7H-pyrrolo...)
Show SMILES Cc1c[nH]c2ncnc(N3CCC(N)(CNC(=O)C(F)(F)F)C3)c12
Show InChI InChI=1S/C14H17F3N6O/c1-8-4-19-10-9(8)11(22-7-21-10)23-3-2-13(18,6-23)5-20-12(24)14(15,16)17/h4,7H,2-3,5-6,18H2,1H3,(H,20,24)(H,19,21,22)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 61n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of AKT1 after 90 mins by IMAP assay

J Med Chem 53: 4615-22 (2010)


Article DOI: 10.1021/jm1003842
BindingDB Entry DOI: 10.7270/Q24X580C
More data for this
Ligand-Target Pair