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Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50347958'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase


(Homo sapiens (Human))
BDBM50347958
PNG
(CHEMBL1800146)
Show SMILES [#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#6])-[#6])-[#6](-[#7])=O |r|
Show InChI InChI=1S/C45H79N15O8/c1-4-10-32(39(64)59-35(24-28-16-18-29(61)19-17-28)42(67)60-36(25-46)43(68)55-31(37(48)62)20-15-26(2)3)56-40(65)33(14-9-22-54-45(51)52)57-41(66)34(23-27-11-6-5-7-12-27)58-38(63)30(47)13-8-21-53-44(49)50/h16-19,26-27,30-36,61H,4-15,20-25,46-47H2,1-3H3,(H2,48,62)(H,55,68)(H,56,65)(H,57,66)(H,58,63)(H,59,64)(H,60,67)(H4,49,50,53)(H4,51,52,54)/t30-,31-,32-,33-,34-,35-,36-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 950n/an/an/an/an/an/a



The Hebrew University of Jerusalem

Curated by ChEMBL


Assay Description
Inhibition of Akt using RPRTSSF peptide and [gamma32]ATP by cell-free radioactive assay


J Med Chem 54: 5154-64 (2011)


Article DOI: 10.1021/jm2003969
BindingDB Entry DOI: 10.7270/Q26D5TBX
More data for this
Ligand-Target Pair