Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase' and Ligand = 'BDBM50528412'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50528412 (CHEMBL4529738) Show SMILES Cn1ncc(Cl)c1-c1coc(c1)C(=O)N[C@@H]1CNCC[C@H]1c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C20H19ClF2N4O2/c1-27-19(14(21)8-25-27)12-7-18(29-10-12)20(28)26-17-9-24-5-4-13(17)11-2-3-15(22)16(23)6-11/h2-3,6-8,10,13,17,24H,4-5,9H2,1H3,(H,26,28)/t13-,17+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human Akt1 expressed in Escherichia coli using STK Substrate 2-biotin as substrate incubated for 1 hr by HTRF assay				J Med Chem 62: 7264-7288 (2019) Article DOI: 10.1021/acs.jmedchem.9b00891 BindingDB Entry DOI: 10.7270/Q2XW4P7W
					More data for this Ligand-Target Pair