Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153702 (2-(4-((4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität Dortmund | Assay Description IC50 determinations for activated Akt1 were measured with the KinEASE assay (Cisbio) according to the manufacturers instructions. The kinases A... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [E49C,C296S,C310S,C344S] (Homo sapiens (Human)) | BDBM153702 (2-(4-((4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 410 | n/a | n/a | n/a | 7.4 | n/a |
Technische Universität Dortmund | Assay Description Labeled Akt1 was diluted to 200 nM in the measurement buffer consisting of 50 mMHEPES pH 7.4, 200 mM NaCl, and 0.01% Triton-X 100. Dilution series of... | ACS Chem Biol 10: 279-88 (2015) Article DOI: 10.1021/cb500355c BindingDB Entry DOI: 10.7270/Q218358G | |||||||||||
More data for this Ligand-Target Pair |