Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'RAC-beta serine/threonine-protein kinase' and Ligand = 'BDBM50243777'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243777 (1-(4-(6-phenyl-7-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4...) Show SMILES CC(=O)N1CCN(CC1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 Show InChI InChI=1S/C38H38N10O/c1-26(49)47-19-21-48(22-20-47)38-40-24-31-23-32(28-7-3-2-4-8-28)34(41-35(31)43-38)29-12-10-27(11-13-29)25-46-17-14-30(15-18-46)36-42-37(45-44-36)33-9-5-6-16-39-33/h2-13,16,23-24,30H,14-15,17-22,25H2,1H3,(H,42,44,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt2 (unknown origin) phosphorylation by HTRF assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50243777 (1-(4-(6-phenyl-7-(4-((4-(5-(pyridin-2-yl)-4H-1,2,4...) Show SMILES CC(=O)N1CCN(CC1)c1ncc2cc(-c3ccccc3)c(nc2n1)-c1ccc(CN2CCC(CC2)c2nnc([nH]2)-c2ccccn2)cc1 Show InChI InChI=1S/C38H38N10O/c1-26(49)47-19-21-48(22-20-47)38-40-24-31-23-32(28-7-3-2-4-8-28)34(41-35(31)43-38)29-12-10-27(11-13-29)25-46-17-14-30(15-18-46)36-42-37(45-44-36)33-9-5-6-16-39-33/h2-13,16,23-24,30H,14-15,17-22,25H2,1H3,(H,42,44,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Akt2 (unknown origin) phosphorylation in human by C33a cells by IPKA assay				Bioorg Med Chem Lett 18: 4186-90 (2008) Article DOI: 10.1016/j.bmcl.2008.05.085 BindingDB Entry DOI: 10.7270/Q2F76CBC
					More data for this Ligand-Target Pair