Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM333640'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM333640 (1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...) Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(CN5CCOCC5)cc(c4)C(F)(F)F)c3)c2cc1OC Show InChI InChI=1S/C29H28F3N5O4S/c1-39-25-14-23-24(15-26(25)40-2)33-17-34-27(23)42-22-5-3-4-20(13-22)35-28(38)36-21-11-18(10-19(12-21)29(30,31)32)16-37-6-8-41-9-7-37/h3-5,10-15,17H,6-9,16H2,1-2H3,(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a
AMBIT BIOSCIENCES CORPORATION US Patent					Assay Description Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....				US Patent US9730937 (2017) BindingDB Entry DOI: 10.7270/Q2M32XVC
					More data for this Ligand-Target Pair