Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50077978'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50077978 (4-(5-Biphenyl-4-yl-2-phenyl-3H-imidazol-4-yl)-pyri...) Show SMILES c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(cc1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C26H19N3/c1-3-7-19(8-4-1)20-11-13-21(14-12-20)24-25(22-15-17-27-18-16-22)29-26(28-24)23-9-5-2-6-10-23/h1-18H,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human RAF proto-oncogene serine/threonine-protein kinase				J Med Chem 42: 2180-90 (1999) Article DOI: 10.1021/jm9805236 BindingDB Entry DOI: 10.7270/Q2Q81C8D
					More data for this Ligand-Target Pair