Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340263'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340263 (7-(2-(3-(2-(2-(dimethylamino)ethoxy)-5-(trifluorom...) Show SMILES CNC(=O)c1cc2ccc(CCNC(=O)Nc3cc(ccc3OCCN(C)C)C(F)(F)F)cc2cn1 Show InChI InChI=1S/C25H28F3N5O3/c1-29-23(34)21-13-17-5-4-16(12-18(17)15-31-21)8-9-30-24(35)32-20-14-19(25(26,27)28)6-7-22(20)36-11-10-33(2)3/h4-7,12-15H,8-11H2,1-3H3,(H,29,34)(H2,30,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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