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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340276'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50340276
PNG
(CHEMBL1760636 | N-(6-(2-(3-(3-chloro-4-methylpheny...)
Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3ccc(C)c(Cl)c3)cc2[nH]1
Show InChI InChI=1S/C19H20ClN5O2/c1-11-3-5-14(10-15(11)20)23-19(27)21-8-7-13-4-6-16-17(9-13)25-18(24-16)22-12(2)26/h3-6,9-10H,7-8H2,1-2H3,(H2,21,23,27)(H2,22,24,25,26)
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Merck Serono

Curated by ChEMBL


Assay Description
Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting

Bioorg Med Chem Lett 21: 2264-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.108
BindingDB Entry DOI: 10.7270/Q2MS3T23
More data for this
Ligand-Target Pair