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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340283'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50340283
PNG
(CHEMBL1760643 | N-(6-(2-(3-(2-(2-aminoethoxy)-4-ch...)
Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3cc(C)c(Cl)cc3OCCN)cc2[nH]1
Show InChI InChI=1S/C21H25ClN6O3/c1-12-9-18(19(11-15(12)22)31-8-6-23)28-21(30)24-7-5-14-3-4-16-17(10-14)27-20(26-16)25-13(2)29/h3-4,9-11H,5-8,23H2,1-2H3,(H2,24,28,30)(H2,25,26,27,29)
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Merck Serono

Curated by ChEMBL


Assay Description
Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting

Bioorg Med Chem Lett 21: 2264-9 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.108
BindingDB Entry DOI: 10.7270/Q2MS3T23
More data for this
Ligand-Target Pair