Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50187217'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50187217 (2,4-dichloro-6-{[(2S)-2-(2H-tetrazol-5-yl)pyrrolid...) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)N1CCC[C@H]1c1nnn[nH]1 Show InChI InChI=1S/C11H11Cl2N5O3S/c12-6-4-7(13)10(19)9(5-6)22(20,21)18-3-1-2-8(18)11-14-16-17-15-11/h4-5,8,19H,1-3H2,(H,14,15,16,17)/t8-/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				J Med Chem 49: 3052-5 (2006) Article DOI: 10.1021/jm060168g BindingDB Entry DOI: 10.7270/Q2M04517
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