Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase' and Ligand = 'BDBM50537570'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepatitis C virus)	BDBM50537570 (CHEMBL474496) Show SMILES OC(=O)C(\O)=C\C(=O)c1cccc(OCc2cc(Cl)cc(Cl)c2C#N)c1 Show InChI InChI=1S/C18H11Cl2NO5/c19-12-4-11(14(8-21)15(20)6-12)9-26-13-3-1-2-10(5-13)16(22)7-17(23)18(24)25/h1-7,23H,9H2,(H,24,25)/b17-7-	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibitory activity against HIV-1 wild-type reverse transcriptase.				Eur J Med Chem 164: 576-601 (2019) Article DOI: 10.1016/j.ejmech.2018.12.045 BindingDB Entry DOI: 10.7270/Q2RR224D
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