Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50425529'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50425529 (CHEMBL2313648) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)n1ccc2cc(ccc12)C(O)=O Show InChI InChI=1S/C18H17NO4S/c1-11-8-12(2)17(13(3)9-11)24(22,23)19-7-6-14-10-15(18(20)21)4-5-16(14)19/h4-10H,1-3H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay				J Med Chem 56: 952-62 (2013) Article DOI: 10.1021/jm3014162 BindingDB Entry DOI: 10.7270/Q2D21ZX3
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