Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Rap guanine nucleotide exchange factor 4' and Ligand = 'BDBM50425538'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rap guanine nucleotide exchange factor 4 (Homo sapiens (Human))	BDBM50425538 (CHEMBL2313640) Show SMILES CCc1cccn1S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C13H15NO2S/c1-3-12-5-4-10-14(12)17(15,16)13-8-6-11(2)7-9-13/h4-10H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Medical Branch Curated by ChEMBL					Assay Description Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assay				J Med Chem 56: 952-62 (2013) Article DOI: 10.1021/jm3014162 BindingDB Entry DOI: 10.7270/Q2D21ZX3
					More data for this Ligand-Target Pair