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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ras guanyl-releasing protein 3' and Ligand = 'BDBM50280753'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ras guanyl-releasing protein 3


(Homo sapiens (Human))		BDBM50280753
PNG
(CHEMBL4167900)
Show SMILES CC(C)Cn1cc(\C=C2/CC(CO)(COC(=O)C(C)(C)C)OC2=O)c2ccccc12
Show InChI InChI=1S/C24H31NO5/c1-16(2)12-25-13-18(19-8-6-7-9-20(19)25)10-17-11-24(14-26,30-21(17)27)15-29-22(28)23(3,4)5/h6-10,13,16,26H,11-12,14-15H2,1-5H3/b17-10+
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Similars
Article
PubMed
 3n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation counting

J Med Chem 61: 6261-6276 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00661
BindingDB Entry DOI: 10.7270/Q28P632D
More data for this
Ligand-Target Pair