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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ras guanyl-releasing protein 3' and Ligand = 'BDBM50280771'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ras guanyl-releasing protein 3


(Homo sapiens (Human))		BDBM50280771
PNG
(CHEMBL4160540)
Show SMILES CCCCn1cc(\C=C2/CC(CO)(COC(=O)C(C)(C)C)OC2=O)c2ccccc12
Show InChI InChI=1S/C24H31NO5/c1-5-6-11-25-14-18(19-9-7-8-10-20(19)25)12-17-13-24(15-26,30-21(17)27)16-29-22(28)23(2,3)4/h7-10,12,14,26H,5-6,11,13,15-16H2,1-4H3/b17-12+
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Similars
Article
PubMed
 1.90n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Displacement of [3H]PDBu from full length MBP-tagged human RasGRP3 expressed in Escherichia coli BL21 (DE3) after 5 mins by scintillation counting

J Med Chem 61: 6261-6276 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00661
BindingDB Entry DOI: 10.7270/Q28P632D
More data for this
Ligand-Target Pair