Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391724 (3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Heptares Therapeutics Limited US Patent | Assay Description Radioligand binding assay. Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended i... | US Patent US10888561 (2021) BindingDB Entry DOI: 10.7270/Q28S4T1X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor activity-modifying protein 1 (Homo sapiens (Human)) | BDBM391724 (3,5-dibromo-Nalpha-{[4-(2- | US10300056, Example 9...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research | Assay Description Human CGRP receptors expressed (consisting of CRLR and RAMP1) in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM... | Bioorg Med Chem Lett 18: 3641-5 (2008) BindingDB Entry DOI: 10.7270/Q2T155ZX | |||||||||||
More data for this Ligand-Target Pair |